A G protein γ subunit peptide stabilizes a novel muscarinic receptor state
نویسندگان
چکیده
منابع مشابه
G protein antagonists. A novel hydrophobic peptide competes with receptor for G protein binding.
A substance P (SP) analog, [D-Pro4,D-Trp7,9,10] SP4-11, is known to inhibit the actions of various structurally unrelated messenger molecules as well as SP. Our studies on the effects of this peptide on the regulation of purified G proteins by receptor showed that at least some of the biological effects of the peptide can be explained by the ability of the peptide to block the activation of G p...
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ژورنال
عنوان ژورنال: Biochemical and Biophysical Research Communications
سال: 2006
ISSN: 0006-291X
DOI: 10.1016/j.bbrc.2006.01.093